Bontril - Phendimetrazine

Other names: Adipost, Anorex-SR, Appecon, Bontril PDM, Bontril Slow-Release, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex

What is the most important information I should know about Bontril?
• Use caution when driving, operating machinery, or performing other hazardous activities. Bontril may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities.
• Bontril is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually.
• Do not crush, chew, or open any "once-daily" phendimetrazine tablets or capsules. Swallow them whole.

What is Bontril?
• Bontril is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an "anorectic" or "anorexigenic" drug. Bontril stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.
• Bontril is used as a short-term supplement to diet and exercise in the treatment of obesity.
• Bontril may also be used for purposes other than those listed in this medication guide.

Who should not take Bontril?
• You cannot take Bontril if you
· have heart disease or high blood pressure;
· have arteriosclerosis (hardening of the arteries);
· have glaucoma;
· have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; or
· have a history of drug or alcohol abuse.
• Before taking this medication, tell your doctor if you have
· problems with your thyroid,
· an anxiety disorder,
· epilepsy or another seizure disorder, or
· diabetes.
• You may not be able to take Bontril, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.
• It is not known whether Bontril will harm an unborn baby. Do not take Bontril without first talking to your doctor if you are pregnant.
• It is also not known whether Bontril passes into breast milk. Do not take Bontril without first talking to your doctor if you are breast-feeding a baby.

How should I take Bontril?
• Take Bontril exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Bontril is usually taken once a day (sustained release formula) or two to three times daily (immediate-release formula) before meals on an empty stomach.
• Do not take Bontril in the evening because it may cause insomnia.
• Do not crush, chew, or open any "once-daily" phendimetrazine tablets or capsules. Swallow them whole.
• Never take more of this medication than is prescribed for you. Too much Bontril could be very dangerous to your health.
• Store Bontril at room temperature away from moisture and heat.

What happens if I miss a dose?
• Take the missed dose as soon as you remember. However, if it is almost time for your next dose or if it is already evening, skip the missed dose and take only your next regularly scheduled dose. A dose taken too late in the day will cause insomnia. Do not take a double dose of this medication.

What happens if I overdose?
• Seek emergency medical attention.
• Symptoms of a Bontril overdose include restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures.

What should I avoid while taking Bontril?
• Use caution when driving, operating machinery, or performing other hazardous activities. Bontril may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities.
• Do not take Bontril late in the day. A dose taken too late in the day can cause insomnia.

What are the possible side effects of Bontril?
• If you experience any of the following serious side effects, stop taking Bontril and seek emergency medical attention:
· an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
· an irregular heartbeat or very high blood pressure (severe headache, blurred vision); or
· hallucinations, abnormal behavior, or confusion.
• Other, less serious side effects may be more likely to occur. Continue to take Bontril and talk to your doctor if you experience
· restlessness or tremor,
· nervousness or anxiety,
· headache or dizziness,
· insomnia,
· dry mouth or an unpleasant taste in your mouth,
· diarrhea or constipation, or
· impotence or changes in your sex drive.
• Bontril is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Bontril?
• You cannot take Bontril if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days.
• Changes in insulin and other diabetes drug therapies may be necessary during treatment with Bontril.
• Bontril may reduce the effects of guanethidine (Ismelin). This could lead to an increase in blood pressure. Tell your doctor if you are taking guanethidine.
• Before taking this medication, tell your doctor if you are taking a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), doxepin (Sinequan), nortriptyline (Pamelor), imipramine (Tofranil), clomipramine (Anafranil), protriptyline (Vivactil), or desipramine (Norpramin). These drugs may decrease the effects of Bontril.
• Drugs other than those listed here may also interact with Bontril. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.